Anthracycline Cardiotoxicity in Adult Cancer Patients
Published: 17 Septemebr 2024
JACC: CARDIOONCOLOGY State-of-the-Art Review
Since their introduction in the 1960s, anthracyclines have been a significant breakthrough in oncology, introducing dramatic changes in the treatment of solid and hematologic malignancies. Although new-generation targeted drugs and cellular therapies are revolutionizing contemporary oncology, anthracyclines remain the cornerstone of treatment for lymphomas, acute leukemias, and soft tissue sarcomas.
The Role of Nursing in the Delivery of Cardio-Oncology
Published: 17 September 2024.
Springer Nature 2024
Nurses are the “heart of patient care” and in the forefront or the health care delivery for cardio-oncology patients. Nurses play a critical central role in maximizing longitudinal health of cancer patients and survivors through the prevention of cardiovascular complications throughout the patient’s cancer care journey.
ESC Guidelines on Cardio-Oncology
Published: 26 August 2022.
European Heart Journal, Volume 43, Issue 41, 1 November 2022
This is the first European Society of Cardiology (ESC) guideline on cardio-oncology. The aim of this guideline is to help all the healthcare professionals providing care to oncology patients before, during, and after their cancer treatments with respect to their cardiovascular health and wellness. This guideline provides guidance on the definitions, diagnosis, treatment, and prevention of cancer therapy-related CV toxicity, and the management of CV disease caused directly or indirectly by cancer. This area of medicine has limited trials and evidence to base decision making and, where evidence is limited, this guideline provides the consensus of expert opinion to guide healthcare professionals.
Novel Life-Saving Radiotherapy Technology and How it Can be Made Available in the Developing World
Published: 26 June 2020.
Duvern Ramiah. “Novel Life-Saving Radiotherapy Technology and How it Can be Made Available in the Developing World”. Acta Scientific Cancer Biology 4.7 (2020): 24-26.
Baseline cardiovascular risk assessment in cancer patients scheduled to receive cardiotoxic cancer therapies
A Position Statement and new risk assessment tools from the Cardio‐Oncology Study Group of the Heart Failure Association of the European Society of Cardiology in collaboration with the International Cardio‐Oncology Society.
First published: 28 May 2020
This position statement from the Heart Failure Association of the European Society of Cardiology Cardio‐Oncology Study Group in collaboration with the International Cardio‐Oncology Society presents practical, easy‐to‐use and evidence‐based risk stratification tools for oncologists, haemato‐oncologists and cardiologists to use in their clinical practice to risk stratify oncology patients prior to receiving cancer therapies known to cause heart failure or other serious cardiovascular toxicities. Baseline risk stratification proformas are presented for oncology patients prior to receiving the following cancer therapies: anthracycline chemotherapy, HER2‐targeted therapies such as trastuzumab, vascular endothelial growth factor inhibitors, second and third generation multi‐targeted kinase inhibitors for CML targeting BCR‐ABL, multiple myeloma therapies (proteasome inhibitors and immunomodulatory drugs), RAF and MEK inhibitors or androgen deprivation therapies. Applying these risk stratification proformas will allow clinicians to stratify cancer patients into low, medium, high and very high risk of cardiovascular complications prior to starting treatment, with the aim of improving personalised approaches to minimise the risk of cardiovascular toxicity from cancer therapies.
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Cardio-Oncology Services: rationale, organization, and implementation: A report from the ESC Cardio-Oncology council
Euro Heart J. 2019 Jun 7;40(22):1756-1763. doi: 10.1093/eurheartj/ehy453.
Abstract
Aims: Anticancer therapies have extended the lives of millions of patients with malignancies, but for some this benefit is tempered by adverse cardiovascular (CV) effects. Cardiotoxicity may occur early or late after treatment initiation or termination. The extent of this cardiotoxicity is variable, depending on the type of drug used, combination with other drugs, mediastinal radiotherapy, the presence of CV risk factors, and comorbidities. A recent position paper from the European Society of Cardiology addressed the management of CV monitoring and management of patients treated for cancer.